following Aronne's plan from his latest book

"[This is] the new era in weight-loss treatment," continues Apovian. Drugs with combinations like the one Aronne prescribed are working their way through the FDA. Qnexa, a combination of the appetite-suppressant pendants clearance phentermine and topiramate, the generic name for Topamax, was recently submitted for FDA approval. Contrave (buproprion and the addiction drug naltrexone) is slated to be up for approval later this year. Empatic (buproprion and the antiseizure drug zonisamide) is currently in clinical trials.

"We've learned that we may need to combine several different drugs to get a weight-loss drug that works better than what we have available," says Apovian."I was like, Bring it on. I'm not shy about pills," earrings clearance says Grauso, whose migraines abated after she started on Topamax. "My father was a pharmaceutical executive, so we had closets full of Valium. I grew up around drugs. I know the dangers." She's suffered no adverse effects, and the results are clear. "It's like magic."Well -- magic and a little old-fashioned elbow grease: Grauso started an Olympian training regimen, doing Thai boxing and Pilates at Clay, tennis at CityView, and golf at Chelsea Piers. She rides her stallion, Mexicano, at the Grausos' country house in Millbrook, New York. "I was always an athlete, so I love it."

She also cleaned up her diet, following Aronne's plan from his latest book, The Skinny. She now starts off her day with a protein shake (and is allowed to keep her venti lattes). During her daily workouts, she quaffs a two-liter bottle of water with two Emergen-Cs, followed by a second breakfast including protein. She no longer skips lunch, and she eats dinner early, before 7:00 P.M. She didn't, however, have to cut out her nightly glass of wine: "You can't ask me to give up a drink at the end of the day," she says.



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